In immediately’s health-conscious world, dietary dietary supplements have change into a well-liked instrument for filling dietary gaps, bettering general well-being, and even managing particular well being situations. Nevertheless, not all dietary supplements are created equal. Some will be contaminated, work together with medicines, and even hurt liver well being. Choosing the proper complement requires cautious consideration and consciousness of potential dangers, and it additionally means being conscious of shady advertising techniques!
‘Dietary supplements’ is an umbrella time period for supplemental types of particular person vitamins like calcium and iron. However the extra problematic of the bunch are ‘pure’ dietary dietary supplements which can be marketed with shady claims, proprietary formulation, and little to no testing. These are the varieties of dietary supplements that I’m principally referring to on this publish.
The Hidden Risks of Dietary supplements: Liver Failure, Current Analysis, and How one can Keep Secure
Dietary dietary supplements are a multi-billion-dollar trade, marketed as a simple method to enhance well being, improve vitality, and fill in dietary gaps. Nevertheless, behind the shiny labels and well being claims, a rising physique of analysis reveals that some dietary supplements can pose critical well being dangers—together with liver failure.


Lately, instances of supplement-induced liver damage (SILI) have been on the rise, with sure natural and dietary dietary supplements linked to extreme liver injury, hospitalization, and even dying. Regardless of being extensively accessible over-the-counter and sometimes perceived as “pure” and secure, many dietary supplements are poorly regulated and might include dangerous elements.
Complement Advertising is a Dumpster Hearth
‘However it’s pure!’ So are toxic mushrooms, however no one needs to eat these. The complement trade – specifically the diet complement trade – is constructed on convincing individuals to purchase dietary supplements that we truly don’t want.
Implying that dietary supplements are extra ‘pure’ than medicines works on the Attraction to Nature fallacy, which complement makers use to make their product seem safer than prescription drugs. As a dietitian, I’m seeing this quite a bit with GLP-1 dietary supplements, that are principally simply rubbish. Nothing about them is efficient or safer than precise medicines, that are regulated and prescribed below managed situations (ideally…everyone knows one thing who’s getting them from doubtful sources).
I used to be unreasonably blissful to see that Kourtney Kardashian’s Lemme GLP-1 complement is at the moment the topic of a category motion lawsuit for claiming to work like GLP-1 agonist remedy. It doesn’t. However as I wrote in one in all my current posts, there are various individuals who need GLP-1 remedy however can’t afford it. This leaves a niche that’s being grossly exploited by the complement trade.


That’s how shady complement makers earn their cash, and it typically works…to the tune of $177 billion {dollars} in 2023, and projected to develop exponentially for the forseeable future. Whether or not it’s weight reduction, menopause, blood sugar (see my Glucose Goddess Anti Spike evaluation right here), immunity-boosting, or no matter else, the complement trade has a capsule for that.
It goes with out saying that if a complement is claiming to remedy nervousness or despair or every other psychological well being analysis, it’s an enormous purple flag. Claims like these are unethical and probably harmful, as they’ll persuade individuals to desert efficient and crucial remedy.
Getting clever to complement advertising scams takes a number of small checks.
Diet Complement Crimson Flags:
No analysis, or basing claims on animal or cell analysis. Even in case you aren’t well-versed in studying analysis, all the time check out the complement’s web site to see if it gives analysis to again up its claims. Is the analysis completed on people? Animals? How outdated are the research? Is the analysis completed on the product itself, or solely on sure elements that the product incorporates?
I wrote a publish about the fundamentals of decoding diet analysis right here, however the TL;DR is that you really want current research (as in, final 5 years), completed in people, printed in peer-reviewed journals, on the product itself. 99% of the time, you received’t discover all of these issues. That may be a purple flag.
Something offered by multi-level advertising. Not solely do MLM corporations prey on susceptible individuals (primarily girls), they have a tendency to take advantage of egregious claims about their merchandise. MLM salespeople aren’t skilled to present diet recommendation or perceive your well being historical past. Belief me – if one thing groundbreaking exists, will probably be regulated by the FDA and offered in drugstores, not by some MLM coach.


Implying that their formulation was found by ‘Harvard (or X Ivy League) scientists’ or that Huge Pharma/precise scientists haven’t but found this groundbreaking secret. I see this quite a bit from corporations like VShred (learn my VShred evaluation right here) and Lifevantage (learn my Lifevantage Protandim and GLP-1 evaluation right here), amongst many others. There isn’t any large secret. No one is hiding something (apart from these corporations making an attempt to cover their grift, though they aren’t fooling me!). Identify dropping an Ivy League faculty by no means means something, both. It’s all bluster created to present them false legitimacy.
Claiming {that a} complement can remedy the incurable, akin to autism, ADHD. Don’t even go there.
Huge claims and use of statistics that appear too good to be true. 95% of individuals love this complement? How did the corporate even decide that? Trace: they didn’t.


The usage of earlier than and after images and testimonials to ‘show’ efficacy of a product. These are simply faked, they usually present up when an organization has nothing higher to supply by way of proof of their product working.
The declare of being safer, extra pure, or equally efficient as precise medicines. We talked about this above.


Obscure claims utilizing phrases or phrases like ‘helps metabolism’ or ‘helps with X’. That is how corporations could make the claims they make, with out triggering the FDA’s consideration. It’s a loophole that many individuals don’t learn about, however now you do!
The usage of influencers to promote the product. This one is perhaps controversial, however I really feel like widespread influencers utilizing affiliate codes to flood peoples’ social feeds with adverts for a product is a distraction and made to persuade potential prospects that in the event that they use the product, they’ll be younger/enticing/wholesome/widespread just like the individuals promoting it.
The Risks of Diet Dietary supplements
Whereas all diet dietary supplements are marketed as useful, they’ll typically do extra hurt than good. Among the key dangers embody:
Lack of Regulation
The U.S. Meals and Drug Administration (FDA) regulates dietary supplements below the Dietary Complement Well being and Schooling Act (DSHEA) of 1994, which permits producers to promote merchandise with out proving their security or efficacy. Not like pharmaceuticals, dietary dietary supplements aren’t required to endure rigorous testing earlier than hitting the market.
Which means:
Dietary supplements could include unlisted or dangerous elements.
Dosages could also be inconsistent or greater than really helpful.
Contaminants akin to heavy metals, pesticides, or pharmaceuticals could also be current.
The FDA sometimes doesn’t become involved except there has truly been hurt completed to an individual by the complement.


Liver Toxicity and Organ Harm
The liver performs an important position in processing dietary supplements, breaking down compounds, and detoxifying dangerous substances. Nevertheless, sure dietary supplements include elements that may overwhelm or injury liver cells, resulting in:
Hepatotoxicity (liver toxicity): The liver struggles to course of poisonous compounds, resulting in irritation and cell injury.
Acute liver failure: Extreme instances the place the liver loses its skill to perform, typically requiring a transplant or leading to dying.
Persistent liver illness: Lengthy-term injury from repeated publicity to dangerous dietary supplements.
Harmful Interactions with Drugs
Many individuals take dietary supplements alongside prescription medicines with out realizing that sure combos will be poisonous.
For instance, St. John’s Wort can cut back the effectiveness of antidepressants and contraception capsules. Kava and inexperienced tea extracts have been linked to extreme liver injury, particularly when taken with different medicines metabolized by the liver. Vitamin A and iron in extreme doses could cause liver irritation and injury.
Current Analysis on Complement-Induced Liver Failure
Over the previous decade, scientific research and scientific reviews have highlighted a regarding rise in supplement-related liver damage.


The DILIN Research (2014 – Current)
The Drug-Induced Liver Damage Community (DILIN), a U.S.-based analysis initiative, has been monitoring instances of drug- and supplement-related liver damage.
Their findings present that:
Natural and dietary dietary supplements account for 20% of liver damage instances within the U.S.
The speed of supplement-induced liver injury has elevated from 7% in 2004 to twenty% lately.
Weight-loss and bodybuilding dietary supplements are probably the most generally implicated.
Inexperienced Tea Extracts and Hepatotoxicity
Inexperienced tea extract is a well-liked complement discovered in lots of weight-loss merchandise, however analysis has linked it to extreme liver toxicity.
A 2018 examine within the journal Hepatology discovered that catechins, the lively compounds in inexperienced tea, could cause liver injury in excessive doses. Some instances resulted in acute liver failure requiring transplants. A 2022 examine discovered garcinia cambogia, with or with out inexperienced tea (I’ve seen numerous dietary supplements that include each of those elements) could cause average to extreme liver damage.


Bodybuilding Dietary supplements and Undisclosed Steroids
Bodybuilding dietary supplements are among the many most harmful, with many containing undeclared anabolic steroids that may trigger liver toxicity.
A 2017 examine in The Journal of Gastroenterology and Hepatology discovered that:
Almost 50% of liver damage instances in younger males have been linked to bodybuilding dietary supplements.
Many of those dietary supplements contained unlawful or undisclosed steroid compounds.
Heavy metals like arsenic, micro organism and fungi, banned stimulants like ephedrine, and undeclared medicine like sibutramine (discovered to have cardiac dangers) are only some examples of what has just lately been present in natural diet dietary supplements.
Whereas not all dietary supplements are dangerous, it’s important to method them with warning. Right here’s how one can shield your self:
Do Your Analysis Earlier than Taking Any Complement
Search for scientific research that assist the security and effectiveness of a complement.
Be skeptical of merchandise that promise speedy weight reduction, excessive muscle acquire, or “detox” advantages. If one thing is promising to do what no different complement or remedy has completed earlier than (ie fats burners), stroll or scroll proper on by. Whereas a complement may not be harmful, I additionally contemplate the monetary impacts of taking something you don’t really want.


Select Third-Get together Examined Dietary supplements
For the reason that FDA doesn’t regulate dietary supplements strictly, search for third-party testing from organizations akin to:
U.S. Pharmacopeia (USP)
NSF Worldwide
ConsumerLab
These certifications make sure that dietary supplements include what they declare and would not have dangerous contaminants.
Keep away from Excessive-Threat Dietary supplements
Among the most harmful dietary supplements embody:
Inexperienced tea extract (excessive doses)
Kava
Kratom
Bodybuilding dietary supplements with steroids
Weight-loss dietary supplements with “fats burners” or stimulants
Discuss to Your Physician Earlier than Utilizing Dietary supplements
In case you are on medicines, ask your physician about doable complement interactions.
In case you have liver illness, diabetes, or coronary heart situations, be further cautious with dietary supplements.
In Brief:
Dietary dietary supplements will be useful in some instances, however additionally they pose vital dangers—particularly to liver well being. With analysis linking sure dietary supplements to liver failure, it’s essential to learn and selective about what you are taking.
By selecting third-party examined merchandise, avoiding high-risk dietary supplements, and prioritizing complete meals, you’ll be able to shield your liver and general well being. All the time seek the advice of with a healthcare skilled earlier than including any new complement to your routine.
Your well being is price greater than a fast repair—keep knowledgeable, and keep secure!